WHOCC
Postal address:
Norwegian Institute of Public Health
WHO Collaborating Centre for Drug Statistics Methodology
Postboks 222 Skøyen
0213 Oslo
Norway

Visiting/delivery address:
Myrens verksted 6H
0473 Oslo
Norway

Tel:  +47 21 07 81 60
E-mail:
 
Copyright/Disclaimer

New search    Hide text from Guidelines

B BLOOD AND BLOOD FORMING ORGANS
B03 ANTIANEMIC PREPARATIONS
B03B VITAMIN B12 AND FOLIC ACID

B03BA Vitamin B12 (cyanocobalamin and analogues)

Hydroxocobalamin for treatment of neuralgia is classified here.
Combinations with liver extract are classified at separate 5th levels using the corresponding 50-series. Combinations with folic acid are classified in this group by using the 50-series.
Combinations indicated for symptomatic treatment of vitamin B12 deficiency are classified in B03BA51.
Vitamin B12, see also:
A11D - Vitamin B1, plain and in combination with vitamin B6 and B12
A11EA - Vitamin B-complex, plain
B03A - Iron preparations

The DDDs are based on maintenance treatment of pernicious anemia. Different DDDs are assigned for oral and parenteral formulations of cyanocobalamin due to great differences in bioavailability.
The DDD for mecobalamin is based on the treatment of peripheral neuropathies.

B03BB Folic acid and derivatives

Folic acid and derivatives in combination with other substances are classified in this group at separate 5th levels using the corresponding 50-series, if folic acid deficiency is the main indication. Folinates, used as antidotes, are classified in V03A. Combinations with iron, see B03AD and B03AE. Folic acid for diagnostic use is classified in V04CX - Other diagnostic agents.
Combinations with vitamin B12 are classified in B03BA.

The DDD for oral folic acid is based on prophylactic use and the parenteral DDD is based on treatment.

Last updated: 2024-01-26