WHOCC
Postal address:
Norwegian Institute of Public Health
WHO Collaborating Centre for Drug Statistics Methodology
Postboks 222 Skøyen
0213 Oslo
Norway

Visiting/delivery address:
Myrens verksted 6H
0473 Oslo
Norway

Tel:  +47 21 07 81 60
E-mail:
 
Copyright/Disclaimer

New search    Hide text from Guidelines

L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS

This group comprises preparations used in the treatment of neoplastic diseases, and immunomodulating agents.
Corticosteroids for systemic use, see H02.


L01 ANTINEOPLASTIC AGENTS

Combination products are classified in L01XY - Combinations of antineoplastic agents, except for combinations of monoclonal antibodies or antibody drug conjugates which are classified in L01FY.
Detoxifying agents used in connection with high dose treatment of antineoplastic agents are classified in V03AF (e.g. calcium folinate).
Radiopharmaceuticals used in the treatment of cancer are classified in V10X.

DDDs have been established for the protein kinase inhibitors in L01E only.
No DDDs have been established for substances classified in ATC 3rd level L01A, L01B, L01C, L01D, L01F or L01X. This is because of highly individualised use and wide dosage ranges. The doses used vary substantially because of various types and severity of neoplastic diseases, and also because of the extensive use of combination therapy.
The consumption of antineoplastic agents is in some countries measured in grams. This is recommended as a method to be used internationally for these particular agents.


L01C PLANT ALKALOIDS AND OTHER NATURAL PRODUCTS

L01CA Vinca alkaloids and analogues

Synthetic analogues are also classified in this group.

L01CB Podophyllotoxin derivatives

Antivirals for topical use, e.g. podophyllotoxin, see D06BB - Antivirals.

L01CC Colchicine derivatives

Colchicine is classified in M04AC01.

L01CD Taxanes

L01CD01 - paclitaxel includes solvent based paclitaxel and paclitaxel albumin.

L01CE Topoisomerase 1 (TOP1) inhibitors

All formulations of irinotecan (e.g. liposomal) are classified in L01CE02.

L01CX Other plant alkaloids and natural products

Last updated: 2024-01-26