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L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS

This group comprises preparations used in the treatment of neoplastic diseases, and immunomodulating agents.
Corticosteroids for systemic use, see H02.


L01 ANTINEOPLASTIC AGENTS

Combination products are classified in L01XY - Combinations of antineoplastic agents, except for combinations of monoclonal antibodies or antibody drug conjugates which are classified in L01FY.
Detoxifying agents used in connection with high dose treatment of antineoplastic agents are classified in V03AF (e.g. calcium folinate).
Radiopharmaceuticals used in the treatment of cancer are classified in V10X.

DDDs have been established for the protein kinase inhibitors in L01E only.
No DDDs have been established for substances classified in ATC 3rd level L01A, L01B, L01C, L01D, L01F or L01X. This is because of highly individualised use and wide dosage ranges. The doses used vary substantially because of various types and severity of neoplastic diseases, and also because of the extensive use of combination therapy.
The consumption of antineoplastic agents is in some countries measured in grams. This is recommended as a method to be used internationally for these particular agents.


L01X OTHER ANTINEOPLASTIC AGENTS

This group comprises antineoplastic preparations which cannot be classified in the preceding groups.


L01XX Other antineoplastic agents

Also antineoplastic agents for dermatological use are classified here.
All asparaginases regardless of origins are classified in L01XX02. The
50-series codes are used for single substances due to lack of numbers.
Phosphatidylinositol-3-kinase (Pi3K) inhibitors are classified in L01EM.


    ATC code  Name  DDD  U Adm.R Note
    L01XX44 aflibercept    

List of abbreviations

Last updated: 2024-01-26