WHOCC
Postal address:
WHO Collaborating Centre for Drug Statistics Methodology
Norwegian Institute of Public Health
P.O.Box 4404 Nydalen
0403 Oslo
Norway

Visiting/delivery address:
Marcus Thranes gate 6
0473 Oslo
Norway

Tel:  +47 21 07 81 60
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ATC alterations from 2005-2017

Cumulative overview of all ATC alterations performed in the period 2005-2017. The year changed is when the alterations were implemented in the ATC/DDD Index.

Previous ATC codeSubstance nameNew ATC codeYear changed
V09AX02cefprozilV09IX042005
B03AB06ferric citrateV03AE082016
A12AA12calcium acetate 11)V03AE072016
G04BE05phentolamineV03AB362011
S01XA17pegaptanibS01LA032007
S01XA16anecortaveS01LA022007
L01XD02verteporfinS01LA012007
S01AX23besifloxacinS01AE082013
S01AX22moxifloxacinS01AE072013
S01AX21gatifloxacinS01AE062013
S01AX19levofloxacinS01AE052013
S01AX17lomefloxacinS01AE042013
S01AX13ciprofloxacinS01AE032013
S01AX12norfloxacinS01AE022013
S01AX11ofloxacinS01AE012013
L04AC06mepolizumabR03DX092017
R03AK04 9)salbutamol and ipratropium bromideR03AL022014
R03AK03fenoterol and ipratropium bromide 8)R03AL012014
R03AK07 10)formoterol and mometasoneR03AK092014
R03AK07 10)formoterol and beclometasoneR03AK082014
P01BE52artemether and lumefantrine 26)P01BF012011
N05AK01tetrabenazineN07XX062008
N02AA09diamorphineN07BC062013
N07BA02bupropionN06AX122009
N05CM17melatoninN05CH012008
N05AX09clotiapineN05AH062010
N01AX01droperidolN05AD08 (existing code)2013
C04AX13ceftriaxone, combinationsN04BC082006
N01AB03methoxyfluraneN02BG092009
N02AA55 21)oxycodone and ibuprofenN02AJ192017
N02BA51 24)oxycodone and acetylsalicylic acidN02AJ182017
N02AA55 21)oxycodone and acetylsalicylic acidN02AJ182017
N02BE51 25)oxycodone and paracetamol N02AJ172017
N02AA55 21)oxycodone and paracetamolN02AJ172017
N02AX52 20)tramadol and paracetamolN02AJ132017
N02BE51 25)codeine and other non-opioid analgesics N02AJ092017
N02AA59 23)codeine and other non-opioid analgesics N02AJ092017
N02AA59 23)codeine and ibuprofenN02AJ082017
M01AE51 19)codeine and ibuprofenN02AJ082017
N02BA51 24)codeine and acetylsalicylic acidN02AJ072017
N02AA59 23)codeine and acetylsalicylic acid N02AJ072017
N02BE51 25)codeine and paracetamol N02AJ062017
N02AA59 23)codeine and paracetamolN02AJ062017
N02AA58 22)dihydrocodeine and other non-opioid analgesicsN02AJ032017
M01AE51 19)dihydrocodeine and other non-opioid analgesicsN02AJ032017
N02AA59 23)dihydrocodeine and acetylsalicylic acid N02AJ022017
N02AA58 22)dihydrocodeine and acetylsalicylic acid N02AJ022017
N02BA51 24)dihydrocodeine and paracetamol N02AJ012017
N02AA55 22)dihydrocodeine and paracetamol N02AJ012017
L01BA01 13)methotrexateL04AX032017
L04AA05tacrolimusL04AD022008
L04AA01ciclosporinL04AD012008
L04AA14anakinraL04AC032008
L04AA09basiliximabL04AC022008
L04AA08daclizumabL04AC012008
L04AA17adalimumabL04AB042008
L04AA16afelimomabL04AB032008
L04AA12infliximabL04AB022008
L04AA11etanerceptL04AB012008
L01XC04alemtuzumabL04AA342015
J05AB54ribavirin, combinationsL03AB60 1)2007
H01CA03histrelinL02AE052013
B01AC14cefdinirL01XX352006
L01XX34erlotinibL01XE032007
L01XX31gefitinibL01XE022007
L01XX28imatinibL01XE012007
J05AE06lopinavir and ritonavirJ05AR102013
J05AF30combinationsJ05AR 2)2007
J01DA37cefacetrileJ01DE022005
J01DA24cefatrizineJ01DE012005
J01DA63cefmetazoleJ01DD542005
J01DA42ceftibutenJ01DD152005
J01DA39ceftezoleJ01DD142005
J01DA33cefapirinJ01DD132005
J01DA32cefpiramideJ01DD122005
J01DA27cefepimeJ01DD112005
J01DA26cefiximeJ01DD102005
J01DA25ceftizoximeJ01DD092005
J01DA23cefotiamJ01DD082005
J01DA22latamoxefJ01DD072005
J01DA18cefazedoneJ01DD062005
J01DA16ceftriaxoneJ01DD052005
J01DA13cefotaximeJ01DD042005
J01DA12cefadroxilJ01DD032005
J01DA11cefaclorJ01DD022005
J01DA10cefamandoleJ01DD012005
J01DA41loracarbefJ01DC102005
J01DA40cefpiromeJ01DC092005
J01DA38cefroxadineJ01DC082005
J01DA19cefmenoximeJ01DC072005
J01DA17cefotetanJ01DC062005
J01DA14ceftazidimeJ01DC052005
J01DA08cefoxitinJ01DC042005
J01DA07cefazolinJ01DC032005
J01DA06cefalotinJ01DC022005
J01DA05cefaloridineJ01DC012005
J01DA36cefpodoximeJ01DB122005
J01DA35cefoperazoneJ01DB112005
J01DA34cefradineJ01DB102005
J01DA31cefetametJ01DB092005
J01DA30cefodizimeJ01DB082005
J01DA21cefonicidJ01DB072005
J01DA15cefsulodinJ01DB062005
J01DA09cefuroximeJ01DB052005
J01DA04cefalexinJ01DB042005
J01DA03cefalotinJ01DB032005
J01DA02cefaloridineJ01DB022005
J01DA01cefalexinJ01DB012005
A11CC07paricalcitol H05BX022010
R05CB12tioproninG04BX162017
G03DC05tiboloneG03CX012008
G03AC03levonorgestrelG03AD01 3)2011
D11AX19alitretinoinD11AH042012
D11AX17cromoglicic acidD11AH032010
D11AX15pimecrolimusD11AH022010
D11AX14tacrolimusD11AH012010
B06AA11bromelainsD03BA032014
C10AA55atorvastatin, combinationsC10BX032006
C10AA53pravastatin, combinationsC10BX022006
C10AA51fludeoxyglucose [18F]C10BX012006
C10AA52anagrelideC10BA012006
C07AB57bisoprolol and acetylsalicylic acid 16)C07FX042017
C07AB52metoprolol and acetylsalicylic acid  15)C07FX032017
C07AA57sotalol and acetylsalicylic acid  14) C07FX022017
C07FA05propranolol and other combinations 17)C07FX012017
C07FB02 18)metoprolol and amlodipine C07FB132017
C07FB02 18)metoprolol and felodipineC07FB022017
D03AX08isosorbide dinitrateC05AE022008
D03AX07glyceryl trinitrateC05AE012008
R03CA02ephedrineC01CA26 4)2011
C01EB12tedisamilC01BD062009
C01EB19icatibantB06AC022012
B02AB03 5)C1-inhibitor, plasma derivedB06AC012012
B03AC07ferric sodium gluconate complexB03AC 7)2014
B03AC06ferric oxide dextran complexesB03AC 7)2014
B03AC05ferric sorbitol gluconic acid complexB03AC 7)2014
B03AC03iron-sorbitol-citric acid complexB03AC 7)2014
B03AC02saccharated iron oxideB03AC 7)2014
B03AC01ferric oxide polymaltose complexesB03AC 7)2014
B02BD12trenonacog alfaB02BD04 12)2017
B02BD09nonacog alfaB02BD04 12)2017
B02BC10fibrinogen, humanB02BC30 6)2014
B01AX06rivaroxabanB01AF012013
C10AX04benfluorexA10BX062009
A10BX12empagliflozinA10BK032017
A10BX11canagliflozinA10BK022017
A10BX09dapagliflozinA10BK012017
A10BX14dulaglutideA10BJ052017
A10BX13albiglutideA10BJ042017
A10BX10lixisenatideA10BJ032017
A10BX07liraglutideA10BJ022017
A10BX04exenatideA10BJ012017
A03AE02tegaserodA06AX062013
A03AE04prucaloprideA06AX052013
1) ATC level name changed to: peginterferon-alfa-2b, combinations
2) Separate ATC 5th levels are established for the different combinations in ATC-gr J05AR Antivirals for treatment of HIV infections, combinations
3) Oral products (packages) only indicated for emergency contraception.
4) Only parenteral formulations.
5) New ATC 5th level name
6) Combinations previously classified in B02BC10 should be altered to B02BC30 combinations (existing code).
7) ATC 5th levels deleted, all products classified on the 4th level only (B03AC Iron, parenteral preparations). The DDD remains unchanged, 0.1 g (P) Fe.
8) Previous ATC level name: fenoterol and other drugs for obstructive airway diseases.
9) Split of code. Combinations of salbutamol and sodium cromoglicate remains in R03AK04.
10) Split of code. Combinations of formoterol and budesonide remains in R03AK07.
11) Previous ATC level name: calcium acetate anhydrous
12) All coagulation factor IX products are classified in ATC code B02BD04.
13) Split of ATC code. Only the classification of pre-filled syringe/pen of methotrexate for use in non-cancer indications is changed. Parenteral products used for treatment of cancer will remain in L01BA01.
14) ATC level name changed from: sotalol, combinations 
15) ATC level name changed from: metoprolol, combinations 
16) ATC level name changed from: bisoprolol, combinations 
17) ATC level name changed from: propranolol and other antihypertensives 
18) Split of ATC code. ATC level name changed from: metoprolol and other antihypertensives. Combinations of metoprolol and felodipine remains in C07FB02. New level name: metoprolol and felodipine 
19) Split of ATC code. The different fixed combinations of ibuprofen and opioid analgesics are given new ATC 5th levels in N02AJ Opioids and non-opioid analgesics. M01AE51 ibuprofen, combinations remains for other combinations.
20) Split of ATC code. ATC level name changed from: tramadol, combinations. The different fixed combinations of tramadol and other analgesics are given new ATC 5th levels in N02AJ Opioids and non-opioid analgesics.
21) Split of ATC code. ATC level name changed from: oxycodone, combinations. The different fixed combinations of oxycodone and other analgesics are given new ATC 5th levels in N02AJ Opioids and non-opioid analgesics. ATC code N02AA55 remains for combinations of oxycodone and naloxone (changed level name).
22) Split of ATC code. The different fixed combinations of dihydrocodeine and other analgesics are given new ATC 5th levels in N02AJ Opioids and non-opioid analgesics. ATC code N02AA58 dihydrocodeine, combinations is maintained for other combinations.
23) Split of ATC code. The different fixed combinations of codeine and other analgesics are given new ATC 5th levels in N02AJ Opioids and non-opioid analgesics. ATC code N02AA59 codeine, combinations is maintained for other combinations.
24) Split of ATC code. The different fixed combinations of acetylsalisylic acid and opioid analgesics are given new ATC 5th levels in N02AJ Opioids and non-opioid analgesics. ATC code N02BA51 acetylsalicylic acid, combinations excl. psycholeptics is maintained for other combinations.
25) Split of ATC code. The different fixed combinations of paracetamol and opioid analgesics are given new ATC 5th levels in N02AJ Opioids and non-opioid analgesics. ATC code N02BE51 paracetamol, combinations excl. psycholeptics is maintained for other combinations.
26) New ATC 5th level name; changed from artemether, combinations (P01BE52).

Last updated: 2017-06-21