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L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTSThis group comprises preparations used in the treatment of neoplastic diseases, and immunomodulating agents.
Corticosteroids for systemic use, see H02.
L01 ANTINEOPLASTIC AGENTS
Combination products are classified in L01XY - Combinations of antineoplastic agents.
Detoxifying agents used in connection with high dose treatment of antineoplastic agents are classified in V03AF (e.g. calcium folinate).
Radiopharmaceuticals used in the treatment of cancer are classified in V10X.
| DDDs have been established for the protein kinase inhibitors in L01E only. No DDDs have been established for substances classified in ATC 3rd level L01A, L01B, L01C, L01D, L01F or L01X. This is because of highly individualised use and wide dosage ranges. The doses used vary substantially because of various types and severity of neoplastic diseases, and also because of the extensive use of combination therapy. The consumption of the antineoplastic agents is in some countries measured in grams. This is recommended as a method to be used internationally for these particular agents. |
L01X OTHER ANTINEOPLASTIC AGENTS
This group comprises antineoplastic preparations which cannot be classified in the preceding groups.
L01XA Platinum compounds
L01XB Methylhydrazines
L01XD Sensitizers used in photodynamic/radiation therapy
L01XF Retinoids for cancer treatment
L01XG Proteasome inhibitors
L01XH Histone deacetylase (HDAC) inhibitors
L01XJ Hedgehog pathway inhibitors
L01XK Poly (ADP-ribose) polymerase (PARP) inhibitors
L01XL Antineoplastic cell and gene therapy
L01XX Other antineoplastic agents
Also antineoplastic agents for dermatological use are classified here.
All asparaginases regardless of origins are classified in L01XX02. The
50-series codes are used for single substances due to lack of numbers.
Phosphatidylinositol-3-kinase (Pi3K) inhibitors are classified in L01EM.
L01XY Combinations of antineoplastic agents
All combinations of antineoplastic agents in L01 - Antineoplastic agents are classified in this group.
Combinations of antineoplastic agents with hyaluronidase are classified at the same 5th level as the combinations of antineoplastic agents without hyaluronidase.
Last updated: 2023-01-23